Document Detail


Scleritis and associated disease.
MedLine Citation:
PMID:  620214     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
One hundred patients (66 women and 34 men) who presented consecutively to Moorfields Eye Hospital with scleral disease underwent medical examination. Thirteen were found to have seropositive rheumatoid arthritis and another 16 also had rheumatoid factor present (Rheumaton test). Autoantibodies were present in 35% of patients, being most common in the elderly and most frequent in cases of necrotising and diffuse scleritis. Although scleral disease is uncommon, it is associated with connective-tissue disorders. Scleritis may be severe and destructive locally, and one series showed that 27% of patients who develop necrotising scleritis are dead from systemic complications within five years. It is therefore important for it to be correctly diagnosed and effectively treated at an early stage.
Authors:
S M Lachmann; B L Hazleman; P G Watson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  1     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1978 Jan 
Date Detail:
Created Date:  1978-03-21     Completed Date:  1978-03-21     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  88-90     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Arthritis, Rheumatoid / complications*
Autoantibodies / analysis
Female
Humans
Inflammation / classification,  drug therapy,  etiology
Male
Middle Aged
Sclera*
Chemical
Reg. No./Substance:
0/Autoantibodies
Comments/Corrections

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