Document Detail

Scintigraphic analysis of the parotid glands in patients with sialorrhea and Parkinson's disease.
MedLine Citation:
PMID:  17855148     Owner:  NLM     Status:  MEDLINE    
Since sialorrhea was initially described, it has been associated with Parkinson's disease (PD) but until now little is known about its pathophysiology. The authors studied parotid gland activity using scintigraphic analysis on 14 PD patients with sialorrhea and in eight healthy persons with matching ages. There was no difference between uptake and intra-glandular distribution by the parotid gland in the two groups but the parotid excretion speed in the PD patients was greater than that observed in healthy individuals. Our results reject the hypothesis of PD productive sialorrhea and point to retention sialorrhea due to the increase of saliva excretion velocity.
Denise Hack Nicaretta; Ana Lucia Zuma de Rosso; Carmelindo Maliska; Milton Melciades Barbosa Costa
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Publication Detail:
Type:  Journal Article     Date:  2007-09-12
Journal Detail:
Title:  Parkinsonism & related disorders     Volume:  14     ISSN:  1353-8020     ISO Abbreviation:  Parkinsonism Relat. Disord.     Publication Date:  2008  
Date Detail:
Created Date:  2008-06-02     Completed Date:  2008-10-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9513583     Medline TA:  Parkinsonism Relat Disord     Country:  England    
Other Details:
Languages:  eng     Pagination:  338-41     Citation Subset:  IM    
25(a) Enfermaria da Santa Casa de Misericórdia do Rio de Janeiro e Serviço de Neurologia do Hospital Universitário Antonio Pedro da Universidade Federal Fluminense (UFF), Brazil.
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MeSH Terms
Case-Control Studies
Middle Aged
Parkinson Disease / complications*
Parotid Gland / radionuclide imaging*
Radionuclide Imaging / methods*
Severity of Illness Index
Sialorrhea / etiology*,  pathology*

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