| Science to practice: what does MR oxygenation imaging tell us about human breast cancer hypoxia? | |
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MedLine Citation:
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PMID: 20032129 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The paradoxical relationship between blood oxygen level-dependent (BOLD) magnetic resonance (MR) imaging and breast cancer hypoxia challenges our current understanding of what we believe is happening to erythrocytes in tumors. The ability of air breathing R2* measurements to reflect tissue hypoxia appears to be tumor type-specific, which should prompt further exploration of this image contrast mechanism in both human and animal tumors. |
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Authors:
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Anwar Padhani |
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Publication Detail:
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Type: Comment; Journal Article |
Journal Detail:
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Title: Radiology Volume: 254 ISSN: 1527-1315 ISO Abbreviation: Radiology Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-12-24 Completed Date: 2010-01-26 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: United States |
Other Details:
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Languages: eng Pagination: 1-3 Citation Subset: AIM; IM |
Affiliation:
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Paul Strickland Scanner Centre, Mount Vernon Cancer Centre, Rickmansworth Road, Northwood, Middlesex HA6 2RN UK. anwar.padhani@stricklandscanner.org.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anoxia / blood*, physiopathology Breast Neoplasms / blood*, diagnosis*, physiopathology Erythrocytes / physiology* Female Humans Magnetic Resonance Imaging / methods* Oxygen / blood* Phenotype Radiopharmaceuticals / diagnostic use Tomography, Emission-Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 7782-44-7/Oxygen |
| Comments/Corrections | |
Comment On:
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Radiology. 2010 Jan;254(1):110-8
[PMID:
20032145
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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