Document Detail

School entry age outcomes for infants with birth weight ≤ 800 grams.
MedLine Citation:
PMID:  20674931     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the mortality and long-term morbidity rates of extremely low birth weight (ELBW) infants admitted to neonatal intensive care units (NICUs).
STUDY DESIGN: This was a longitudinal cohort study of all admissions born between 1983 and 2003 with birth weight ≤ 800 g at a single tertiary NICU. Trends in survival and neurodevelopmental outcome rates at school entry in four 5-year epochs were analyzed.
RESULTS: Of 917 admissions, 552 survived to NICU discharge, with significantly increasing survival rates from 46% in epoch 1 to 71% in epoch 4 (P < .0001). Although the overall impairment rate of 30% did not change, the pattern of impairments did. Cognitive (P = .017) and hearing (P = .014) impairment rates increased. Visual impairment rates decreased (P = .042), with a trend toward decreasing cerebral palsy from 20% to 12% (P = .061).
CONCLUSIONS: Improved survival of low birth weight preterm infants has been associated with different types of neurodevelopmental impairments, including increased cognitive impairment rates.
Anne R Synnes; Shelagh Anson; Astrid Arkesteijn; Arsalan Butt; Ruth E Grunau; Marilyn Rogers; Michael F Whitfield
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-08-03
Journal Detail:
Title:  The Journal of pediatrics     Volume:  157     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-22     Completed Date:  2010-12-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  989-994.e1     Citation Subset:  AIM; IM    
Copyright Information:
Copyright © 2010 Mosby, Inc. All rights reserved.
Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
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MeSH Terms
Age Factors
Developmental Disabilities / epidemiology*
Follow-Up Studies
Infant, Extremely Low Birth Weight*
Infant, Newborn
Survival Rate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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