Document Detail

Schizotypy and mixed-handedness revisited.
MedLine Citation:
PMID:  16112739     Owner:  NLM     Status:  MEDLINE    
Although some previous studies assert that an association between schizotypy and loss of hand dominance is well established, the prevailing use of student populations, small effect sizes and arbitrariness of handedness classification suggest that this tentative association merits further investigation. The association of schizotypy and loss of hand dominance was examined using four samples. The first comprised 353 randomly selected individuals from the general community, the second comprised 131 screened volunteers participating as control subjects in a family study of schizophrenia, the third included 97 full siblings of schizophrenia patients, and the fourth consisted of 176 schizophrenia patients from the same study. The samples of screened volunteers and nonpsychotic siblings were used to replicate results from the community sample and to test the hypothesis that an increase in genetic liability is related to the association of schizotypal traits and mixed handedness. The results demonstrated that mixed handedness and schizotypy traits were unrelated in the representative sample from the community. This finding was replicated in the sample of screened volunteers, while siblings of schizophrenia patients showed a trend in the direction of the hypothesised relationship. In contrast, there was an expected significant but low in magnitude association between loss of hand dominance and the Schizotypal Personality Questionnaire factor of Cognitive Perceptual Dysfunction in schizophrenia patients.
Milan Dragovic; Geoff Hammond; Assen Jablensky
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychiatry research     Volume:  136     ISSN:  0165-1781     ISO Abbreviation:  Psychiatry Res     Publication Date:  2005 Sep 
Date Detail:
Created Date:  2005-09-05     Completed Date:  2006-01-12     Revised Date:  2008-04-17    
Medline Journal Info:
Nlm Unique ID:  7911385     Medline TA:  Psychiatry Res     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  143-52     Citation Subset:  IM    
Centre for Clinical Research in Neuropsychiatry, University of Western Australia, Perth, Australia.
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MeSH Terms
Functional Laterality / physiology*
Middle Aged
Schizotypal Personality Disorder / diagnosis,  epidemiology,  psychology*

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