| Schistosomiasis and pregnancy. | |
| | |
MedLine Citation:
|
PMID: 17336160 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Currently, schistosomes infect approximately 40 million women of child-bearing age, yet little is known about schistosome-associated morbidity in pregnant women and their offspring. Animal models indicate a deleterious effect of schistosome infection on maternal, fetal and neonatal outcomes. Case reports have documented maternal infection in association with poor birth outcomes, and two observational studies indicate that maternal schistosome infection might be associated with decreased birth weight. Rigorously identifying and quantifying the impact of schistosome infection on pregnancy outcomes with well-designed observational and treatment studies are crucial for improving birth outcomes in schistosome-endemic areas. In addition, studies that address the safety of praziquantel during pregnancy could lead to further adoption of the recent informal recommendation by the World Health Organization to treat schistosome-infected pregnant and lactating women. |
| | |
Authors:
|
Jennifer F Friedman; Priya Mital; Hemal K Kanzaria; G Richard Olds; Jonathan D Kurtis |
Publication Detail:
|
Type: Journal Article; Review Date: 2007-03-01 |
Journal Detail:
|
Title: Trends in parasitology Volume: 23 ISSN: 1471-4922 ISO Abbreviation: Trends Parasitol. Publication Date: 2007 Apr |
Date Detail:
|
Created Date: 2007-03-26 Completed Date: 2007-06-07 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100966034 Medline TA: Trends Parasitol Country: England |
Other Details:
|
Languages: eng Pagination: 159-64 Citation Subset: IM |
Affiliation:
|
Center for International Health Research, Rhode Island Hospital, 55 Claverick Street, Providence, RI 02903, USA. jennifer_friedman@brown.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Female Genitalia, Female / parasitology Humans Mice Morbidity Placenta / parasitology Praziquantel / adverse effects*, therapeutic use Pregnancy Pregnancy Complications, Parasitic / epidemiology* Pregnancy Outcome / epidemiology Schistosoma / drug effects, physiology Schistosomiasis / drug therapy, epidemiology* Schistosomicides / adverse effects*, therapeutic use |
| Chemical | |
Reg. No./Substance:
|
0/Schistosomicides; 55268-74-1/Praziquantel |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Complement and coagulation: strangers or partners in crime?
Next Document: Integrating transcriptome, proteome and glycome analyses of Schistosoma biology.