Document Detail


Schistosomiasis in German children.
MedLine Citation:
PMID:  10923230     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Reports on schistosomiasis in children growing up in Europe are rare despite increased travel activity. We report on eight male and three female German children aged 50 months to 15 years with schistosomiasis. Six children were asymptomatic, whereas two presented with typical signs of Katayama fever. Persisting haematuria, headache with eosinophilia and pyelonephritis were observed in one child each. An exposure was reported for six of the children. Two were examined solely because schistosomiasis was diagnosed in a family member. All had antibodies against schistosomal antigens in at least two of three screening tests. However, schistosomal ova (Schistosoma haematobium) were detected in urine and faecal specimens from only three children. A tumour-like lesion of the bladder was found by ultrasound in only one of the children who also exhibited haematuria. Neither eosinophilia nor elevated IgE levels were constant findings. Six to 12 months after praziquantel treatment, parasitological and ultrasound checks were negative and levels of specific antibodies decreased. However, 2 years later, elevated antibody levels were detected in one girl without evidence of any new exposure. She became antibody-negative 1 year after a second course of treatment. CONCLUSION: In contrast to residents of endemic areas, parasitological and ultrasound examinations seem to be inferior to immunodiagnostics in children from non-endemic areas at temporary risk for schistosomiasis.
Authors:
R Bialek; J Knobloch
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of pediatrics     Volume:  159     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2001-01-08     Completed Date:  2001-01-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  530-4     Citation Subset:  IM    
Affiliation:
Institut für Tropenmedizin, Universitätsklinikum Tübingen, Germany. ralf.bialek@med.uni-tuebingen.de
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Africa
Animals
Antibodies, Helminth / blood
Child
Child, Preschool
Female
Follow-Up Studies
Germany
Humans
Male
Parasite Egg Count
Recurrence
Schistosoma haematobium / immunology
Schistosomiasis haematobia / diagnosis,  transmission*
Travel
Chemical
Reg. No./Substance:
0/Antibodies, Helminth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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