| Schistocytic hemolytic anemia owing to central venous catheter in a child with acute lymphoblastic leukemia. | |
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MedLine Citation:
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PMID: 20505536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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SUMMARY: A 4-year-old boy with acute lymphoblastic leukemia (ALL) was inserted a central venous catheter into right vena jugularis interna, whereas on BFM-ALL (Protocol 1) therapy. He developed progressive anemia, thrombocytopenia, schistocytes with triangular or crescent shapes, microspherocytes and teardrop cells in the peripheric blood smear, elevated lactate dehydrogenase, and decreased haptoglobin. Schistocytic hemolytic anemia was considered. On chest radiogram, the central venous catheter (CVC) tip was seen beneath the expected location. An echocardiography revealed that CVC was within the right atrium, in contact with tricuspite leaflets. So, CVC was overhauled and a new one was inserted. After the revision, hemolysis ceased; haptoglobin level normalized. |
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Authors:
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Seda Oztürkmen; Ayşenur Paç; Atilla Senayl; Tuğçin Bora Polat; Ibrahim Ilker Cetin; Zafer Bçakç; Arzu Akyay; Lale Olcay |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric hematology/oncology Volume: 32 ISSN: 1536-3678 ISO Abbreviation: J. Pediatr. Hematol. Oncol. Publication Date: 2010 Aug |
Date Detail:
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Created Date: 2010-08-06 Completed Date: 2010-08-20 Revised Date: 2011-10-06 |
Medline Journal Info:
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Nlm Unique ID: 9505928 Medline TA: J Pediatr Hematol Oncol Country: United States |
Other Details:
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Languages: eng Pagination: e233-5 Citation Subset: IM |
Affiliation:
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Department of Pediatric Hematology, Dr AY Ankara Oncology Training and Research Hospital, Ankara, Turkey. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Hemolytic
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etiology* Antineoplastic Combined Chemotherapy Protocols / therapeutic use Asparaginase / therapeutic use Catheterization, Central Venous / adverse effects* Child, Preschool Daunorubicin / therapeutic use Erythrocytes / pathology* Humans Male Precursor Cell Lymphoblastic Leukemia-Lymphoma / drug therapy* Prednisone / therapeutic use Vincristine / therapeutic use |
| Chemical | |
Reg. No./Substance:
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20830-81-3/Daunorubicin; 53-03-2/Prednisone; 57-22-7/Vincristine; EC 3.5.1.1/Asparaginase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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