| Schisandra chinensis-dependent myocardial protective action of sheng-mai-san in rats. | |
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MedLine Citation:
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PMID: 8982437 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Sheng-Mai-San (SMS), a traditional Chinese formulation used for the treatment of coronary heart disease, is comprised of Radix Ginseng, Fructus Schisandrae and Radix Ophiopogonis. Pretreatment with a lignan-enriched SMS (17 g/kg/day x 3, p.o.) was found effective in protection against isoproterenol-induced myocardial injury in rats, and in ischemia-reperfusion injury in isolated perfused hearts prepared from pretreated animals. Results obtained from pretreatment studies using extracts prepared by mixing various combinations of the three component herbs indicate that the major myocardial protective component in SMS is the lignan-enriched extract of Fructus Schisandrae. |
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Authors:
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P C Li; K T Poon; K M Ko |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The American journal of Chinese medicine Volume: 24 ISSN: 0192-415X ISO Abbreviation: Am. J. Chin. Med. Publication Date: 1996 |
Date Detail:
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Created Date: 1997-03-28 Completed Date: 1997-03-28 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7901431 Medline TA: Am J Chin Med Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 255-62 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Female Heart / drug effects* Male Medicine, Chinese Traditional* Myocardial Ischemia / drug therapy* Rats Rats, Sprague-Dawley |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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