Document Detail


Schilder's disease: Non-invasive diagnosis and successful treatment with human immunoglobulins.
MedLine Citation:
PMID:  21925910     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Schilder's disease (SD) is a rare variant of multiple sclerosis with a predilection to children. It is characterized by focal neurological abnormalities, which are atypical for MS, in conjunction with tumor-like white matter lesions on MRI. We report the case of an 11-year-old girl that demonstrates two important features of the disease: a) the clinical presentation and subsequent course in conjunction with the serial neuroradiological findings stress the feasibility of a non-invasive diagnosis of SD; and b) we report a significant clinical response to treatment with intravenous human Immunoglobulins.
Authors:
Dror Kraus; Osnat Konen; Rachel Straussberg
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-16
Journal Detail:
Title:  European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society     Volume:  -     ISSN:  1532-2130     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9715169     Medline TA:  Eur J Paediatr Neurol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2011 European Paediatric Neurology Society. Published by Elsevier Ltd. All rights reserved.
Affiliation:
Pediatrics A, Schneider Children's Medical Center of Israel, 14 Kaplan St., Petah Tiqwa 49202, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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