Document Detail


Schedule induced self injections of nicotine with recovered body weight.
MedLine Citation:
PMID:  714988     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a recent series of experiments we have shown that high rates of self injection of nicotine were acquired when rats are at 80% body weight on an FT-1 min food delivery schedule. This rate was significantly higher than that of rats at reduced or normal body weight without food delivery schedules or that of rats injecting saline under three parallel control conditions. In the present experiment naive rats were trained to acquire nicotine self injection at 80% body weight with an FT-1 min food delivery schedule. These rats maintained their self injection rates after they were allowed to regain free feeding body weight. The data indicate that once nicotine intake behavior is established it can be maintained with changing nutritional factors.
Authors:
G Singer; F Simpson; W J Lang
Related Documents :
315458 - Antipyretic effect of acetaminophen suppositories in rats.
935218 - Hyperthermia following self-stimulation of the median raphe in the rat.
12144858 - Segmental regulation pattern of body surface temperature in the rat hindlimb.
4698498 - The influence of body temperature on the ventilatory response to co 2 in anaesthetized...
712708 - A freeze-etch study of dense fibres in rat spermatozoa.
11699058 - Mechanisms of phytosterolemia in stroke-prone spontaneously hypertensive and wky rats.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Pharmacology, biochemistry, and behavior     Volume:  9     ISSN:  0091-3057     ISO Abbreviation:  Pharmacol. Biochem. Behav.     Publication Date:  1978 Sep 
Date Detail:
Created Date:  1979-01-15     Completed Date:  1979-01-15     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0367050     Medline TA:  Pharmacol Biochem Behav     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  387-9     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Body Weight
Conditioning, Operant / drug effects*
Nicotine / pharmacology*
Rats
Smoking / psychology
Chemical
Reg. No./Substance:
54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Beta-endorphin is behaviorally active in rats after chronic intravenous administration.
Next Document:  Suppression of fixed-interval responding by flavour-amphetamine pairings in rats.