| Scedosporium apiospermum infection presenting as a pneumothorax and cavitary lung lesions in a patient with acquired immune deficiency syndrome. | |
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MedLine Citation:
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PMID: 20689476 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Scedosporium genus consists of filamentous fungi that inhabit soil, sewage, manure, and polluted waters, and contains two medically important species: Scedosporium apiospermum and Scedosporium prolificans. Scedosporiosis is caused by inhalation or traumatic subcutaneous implantation of the organism, and may have varied clinical presentations. A variety of pulmonary manifestations can occur, but to our knowledge, pneumothorax as initial presentation has not been reported. Treatment may be difficult, as the disease occurs more commonly in immunocompromised patients, and the organism may demonstrate resistance to various antifungal agents. We describe successful treatment of extensive pulmonary disease due to S apiospermum in a patient with acquired immune deficiency syndrome (AIDS). |
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Authors:
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Shirin A Mazumder; Kerry O Cleveland; John Norwood |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Southern medical journal Volume: 103 ISSN: 1541-8243 ISO Abbreviation: South. Med. J. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-09-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0404522 Medline TA: South Med J Country: United States |
Other Details:
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Languages: eng Pagination: 960-2 Citation Subset: AIM; IM |
Affiliation:
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Division of Infectious Diseases, Department of Medicine, University of Tennessee Health Science Center, Memphis, TN, USA. sam7301@yahoo.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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AIDS-Related Opportunistic Infections
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diagnosis,
drug therapy,
microbiology* Adult Antifungal Agents / therapeutic use Female Humans Itraconazole / therapeutic use Lung / microbiology*, radiography Mycetoma / diagnosis*, drug therapy Pneumothorax / drug therapy, microbiology* Pyrimidines / therapeutic use Scedosporium Tomography, X-Ray Computed Triazoles / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 0/Pyrimidines; 0/Triazoles; 0/voriconazole; 84625-61-6/Itraconazole |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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