Document Detail


Scar formation after skin injury to the human foetus in utero or the premature neonate.
MedLine Citation:
PMID:  10343583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A macroscopically visible scar was present at birth in three infants with a history of injury during amniocentesis at 16-20 weeks' gestation. In several neonates born between 21 and 31 weeks' gestation, chemical injury to the skin caused by extravasation of calcium gluconate healed by formation of a large scar. In the infant born at 21 weeks, biopsy of the injured area showed infiltration by large numbers of neutrophils and macrophages. It appears that a very immature neonate can mount a prominent inflammatory reaction and that both a midtrimester foetus and a very immature neonate heal injuries to the skin by scar formation and not by scarless healing.
Authors:
W A Morrison; J V Hurley; T S Ahmad; H R Webster
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of plastic surgery     Volume:  52     ISSN:  0007-1226     ISO Abbreviation:  Br J Plast Surg     Publication Date:  1999 Jan 
Date Detail:
Created Date:  1999-06-03     Completed Date:  1999-06-03     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984714R     Medline TA:  Br J Plast Surg     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  6-11     Citation Subset:  IM    
Affiliation:
Bernard O'Brien Institute of Microsurgery, University of Melbourne, Australia.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Amniocentesis / adverse effects
Cicatrix / embryology,  etiology*,  pathology
Extravasation of Diagnostic and Therapeutic Materials / complications
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / etiology*,  pathology
Male
Skin / embryology,  injuries*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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