| Scanning laser polarimetry in pulmonary tuberculosis patients on chemotherapy. | |
| | |
MedLine Citation:
|
PMID: 16865189 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: The aim of this study was to analyse the thickness of the retinal nerve fibre layer (RNFL) of pulmonary tuberculosis patients on ethambutol and isoniazid. MATERIALS AND METHODS: This was a prospective cohort study where patients with newly diagnosed pulmonary tuberculosis requiring chemotherapy, including ethambutol and isoniazid, were imaged using scanning laser polarimetry. Their mean baseline RNFL thickness and various scanning laser polarimetry parameters of both eyes were measured 2 weeks after the commencement of chemotherapy. The measurements were repeated at 3 months and 6 months after treatment. The various parameters of the baseline and the follow-up measurements were compared using paired sample t-test with Bonferroni correction. RESULTS: Twenty-four patients (16 males and 8 females; mean age, 51.0 +/- 17.6 years) were recruited. There was no statistically significant difference between the baseline and the follow-up measurements in RNFL thickness and all other scanning laser polarimetry parameters. CONCLUSION: In this cohort of subjects, there was no subclinical change in RNFL thickness detected by scanning laser polarimetry in pulmonary tuberculosis patients on chemotherapy, including ethambutol and isoniazid, after 6 months of treatment. |
| | |
Authors:
|
Wilson W T Tang; Jimmy S M Lai; Clement C Y Tham; Kam-Keung Chan; Kin-Sang Chan |
Related Documents
:
|
1716939 - Laser therapy and insertion of wallstents for palliative treatment of esophageal carcin... 3367679 - Combination of laser plus 5-fluorouracil for the treatment of extensive genital condylo... 8976729 - Refractive outcome in eyes with retinopathy of prematurity treated with cryotherapy or ... 17608589 - Effect of er:yag laser combined with rhpdgf-bb on attachment of cultured fibroblasts to... 4084479 - Argon laser trabeculoplasty in exfoliation syndrome. 17225059 - Treatment of 153 japanese patients with q-switched alexandrite laser. 15116039 - In vitro effect of microwave irradiation on the retentive force of magnets. 17283569 - Antiadhesive effect of the mixed solution of sodium hyaluronate and sodium carboxymethy... 10804049 - Factors in neurological deterioration and role of surgical treatment in lumbosacral spi... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Annals of the Academy of Medicine, Singapore Volume: 35 ISSN: 0304-4602 ISO Abbreviation: Ann. Acad. Med. Singap. Publication Date: 2006 Jun |
Date Detail:
|
Created Date: 2006-07-25 Completed Date: 2007-03-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7503289 Medline TA: Ann Acad Med Singapore Country: Singapore |
Other Details:
|
Languages: eng Pagination: 395-9 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Tseung Kwan O Hospital, Kowloon, Hong Kong. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Aged, 80 and over Antitubercular Agents / adverse effects*, therapeutic use Diagnostic Techniques, Ophthalmological Ethambutol / adverse effects*, therapeutic use Female Humans Isoniazid / adverse effects*, therapeutic use Lasers / diagnostic use* Male Middle Aged Prospective Studies Retinal Diseases / chemically induced*, diagnosis* Tuberculosis, Pulmonary / drug therapy* |
| Chemical | |
Reg. No./Substance:
|
0/Antitubercular Agents; 54-85-3/Isoniazid; 74-55-5/Ethambutol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Understanding the super-spreading events of SARS in Singapore.
Next Document: Characterisation of human tear proteins using high-resolution mass spectrometry.