Document Detail

Scanning laser polarimetry and detection of progression after optic disc hemorrhage in patients with glaucoma.
MedLine Citation:
PMID:  12583784     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To examine retinal nerve fiber layer changes with scanning laser polarimetry (SLP) in the eyes of patients with glaucoma and optic disc hemorrhage. METHODS: Automated perimetry and SLP were performed in 17 eyes of 17 patients identified prospectively with optic disc hemorrhage. Criteria for visual field progression were based on decreased sensitivity seen at 3 adjacent points on the total deviation plot. Progression on SLP images was defined as a 15% or more decrease in the average thickness of the affected quadrant (superior or inferior), a 25% or more reduction in the affected quadrant ratio, an increase in the nerve fiber analyzer number of 10 or more (GDx Nerve Fiber Analyzer; Laser Diagnostic Technologies), or any change on Serial Analysis of the SLP images. MAIN OUTCOME MEASURES: Visual field progression and SLP image progression. RESULTS: The mean follow-up was 31 months (minimum, 12 months). Of the 17 eyes, 10 (59%) had visual field progression. No significant change was seen on SLP images for either the total group or the group with visual field progression. Five eyes (29%) showed progression on SLP images, 3 of which also showed visual field progression. Ten eyes showed progression on SLP images that was not confirmed on subsequent imaging. CONCLUSIONS: In eyes with visual field progression after optic disc hemorrhage, a significant change in the SLP image was not seen. Fluctuation of SLP results in patients with glaucoma necessitates confirmation of progression seen on SLP images.
Michael D Boehm; Chad Nedrud; David S Greenfield; Philip P Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Archives of ophthalmology     Volume:  121     ISSN:  0003-9950     ISO Abbreviation:  Arch. Ophthalmol.     Publication Date:  2003 Feb 
Date Detail:
Created Date:  2003-02-13     Completed Date:  2003-02-24     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  7706534     Medline TA:  Arch Ophthalmol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  189-94     Citation Subset:  AIM; IM    
Department of Ophthalmology, University of Washington, Campus Box 356485, 1959 NE Pacific St, Seattle, WA 98195-6485, USA.
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MeSH Terms
Diagnostic Techniques, Ophthalmological
Disease Progression
Glaucoma, Open-Angle / diagnosis*,  physiopathology
Lasers / diagnostic use
Nerve Fibers / pathology*
Optic Disk / pathology*
Optic Nerve Diseases / diagnosis*,  physiopathology
Prospective Studies
Retinal Ganglion Cells / pathology*
Retinal Hemorrhage / complications*,  physiopathology
Vision Disorders / diagnosis,  etiology,  physiopathology
Visual Fields
Grant Support

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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