Document Detail

Scanning electron microscopic observations on cells grown in vitro. VII. HeLa cells can penetrate Wi38 fibroblasts.
MedLine Citation:
PMID:  6698044     Owner:  NLM     Status:  MEDLINE    
When HeLa cells are seeded on a preexisting monolayer of Wi38 fibroblasts, the HeLa cells "try" to get into direct contact with the glass substrate. Once on top of a flat fibroblast the HeLa cell can either migrate from the fibroblast to settle between two fibroblasts on glass or somehow stimulate the underlying cells to retract. In a few cases the HeLa cell directly penetrates the fibroblast, "melting" its way through the underlying cell. The mechanism of this phenomenon which has never been described before in this combination is discussed.
R Benke; N Paweletz
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  European journal of cell biology     Volume:  33     ISSN:  0171-9335     ISO Abbreviation:  Eur. J. Cell Biol.     Publication Date:  1984 Jan 
Date Detail:
Created Date:  1984-04-25     Completed Date:  1984-04-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7906240     Medline TA:  Eur J Cell Biol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  52-4     Citation Subset:  IM    
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MeSH Terms
Cell Communication*
Cells, Cultured
Fibroblasts / ultrastructure*
Hela Cells / ultrastructure*
Lung / cytology,  embryology
Microscopy, Electron, Scanning

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