Document Detail


Scandium-catalyzed regio- and stereospecific methylalumination of silyloxy/alkoxy-substituted alkynes and alkenes.
MedLine Citation:
PMID:  19954187     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Various alkynes and alkenes having a tethered ether group undergo methylalumination reactions with unprecedented regio- and stereoselectivity in the presence of a cationic half-sandwich alkylscandium species as a catalyst. The oxygen atom of the ether group plays an important role in controlling the selectivity, possibly by coordinating to the metal center. Even when a bulky tert-butyl(diphenyl)silyloxy group is used as the tether group, there is no loss of selectivity.
Authors:
Masanori Takimoto; Saori Usami; Zhaomin Hou
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of the American Chemical Society     Volume:  131     ISSN:  1520-5126     ISO Abbreviation:  J. Am. Chem. Soc.     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-12-23     Completed Date:  2010-03-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7503056     Medline TA:  J Am Chem Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  18266-8     Citation Subset:  IM    
Affiliation:
Organometallic Chemistry Laboratory, RIKEN Advanced Science Institute, 2-1 Hirosawa, Wako, Saitama 351-0198, Japan.
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MeSH Terms
Descriptor/Qualifier:
Alkenes / chemistry*
Alkynes / chemistry*
Catalysis
Ether, Ethyl
Organometallic Compounds
Scandium
Silanes
Stereoisomerism
Chemical
Reg. No./Substance:
0/Alkenes; 0/Alkynes; 0/Organometallic Compounds; 0/Silanes; 0/methylaluminum dichloride; 60-29-7/Ether, Ethyl; 7440-20-2/Scandium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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