| Scan-rescan and intra-observer variability of magnetic resonance imaging of carotid atherosclerosis at 1.5 T and 3.0 T. | |
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MedLine Citation:
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PMID: 19001690 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Carotid atherosclerosis measurements for eight subjects at baseline and 14 +/- 2 days later were examined using 1.5 T and 3.0 T magnetic resonance imaging (MRI). A single observer blinded to field strength, subject and timepoint manually segmented carotid artery wall and lumen boundaries in randomized images in five measurement trials. Mean increases in the signal-to-noise ratios (SNR) for T1-weighted images acquired at 3.0 T compared to 1.5 T were 90% (scan) and 80% (rescan). Despite significantly improved SNR and contrast-to-noise ratios (CNR) for images acquired at 3.0 T, vessel wall volume (VWV) intra-observer variability was not significantly different using coefficients of variation (COV), and intraclass correlation coefficients (ICC). VWV interscan variability and consistency at both field strengths were not statistically different (1.5 T/3.0 T COV = 5.7%/7.8%, R(2) = 0.96 for 1.5 T and R(2) = 0.87 for 3.0 T). A two-way analysis of variance showed a VWV dependence on field strength but not scan timepoint. In addition, a paired t-test showed significant differences in VWV measured at 3.0 T as compared to 1.5 T. These results suggest that although images acquired at 1.5 T have lower SNR and CNR VWV, measurement variability was not significantly different from 3.0 T VWV and that VWV is field-strength dependent which may be an important consideration for longitudinal studies. |
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Authors:
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Arvin Vidal; Yves Bureau; Trevor Wade; J David Spence; Brian K Rutt; Aaron Fenster; Grace Parraga |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2008-11-12 |
Journal Detail:
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Title: Physics in medicine and biology Volume: 53 ISSN: 0031-9155 ISO Abbreviation: Phys Med Biol Publication Date: 2008 Dec |
Date Detail:
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Created Date: 2008-11-12 Completed Date: 2009-02-12 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0401220 Medline TA: Phys Med Biol Country: England |
Other Details:
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Languages: eng Pagination: 6821-35 Citation Subset: IM |
Affiliation:
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Imaging Research Laboratories, Robarts Research Institute, 100 Perth Drive, London, N6A 5K8 Canada. avidal@imaging.robarts.ca |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Analysis of Variance Carotid Arteries / pathology* Carotid Artery Diseases / pathology* Contrast Sensitivity Female Humans Linear Models Magnetic Resonance Imaging* / instrumentation, methods Male Middle Aged Observer Variation |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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