Document Detail

Scan-directed unilateral neck exploration for primary hyperparathyroidism: eight-year results from a regional hospital.
MedLine Citation:
PMID:  19342737     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To determine the results of scan-directed unilateral neck exploration for primary hyperparathyroidism. DESIGN: Retrospective study. SETTING: Regional hospital, Hong Kong. PATIENTS: Patients who underwent parathyroid surgery for primary hyperparathyroidism between January 2000 and December 2007 were included. MAIN OUTCOME MEASURES: The demographic, imaging, biochemical, and pathological data, as well as surgical outcomes were analysed according to the treatment received. RESULTS: A total of 78 patients were included in this study; 65 underwent unilateral neck exploration with image guidance by ultrasonography or technetium Tc99m sestamibi scan. The scan sensitivity for localising the side of the lesion was 66% for ultrasound scans, 71% for technetium Tc99m sestamibi scans, and 85% for both scans used in combination. Pathological analysis showed that 95% (74/78) of the patients had a single parathyroid adenoma, two had hyperplasia of four glands, one had a double adenoma, and one a parathyroid carcinoma. Among the patients undergoing scan-directed unilateral neck exploration, one defaulted follow-up, while the remaining 64 patients achieved normal calcium levels at a median follow-up of 6 months. CONCLUSION: Scan-directed unilateral neck exploration is a safe alternative form of treatment for patients with primary hyperparathyroidism, with a cure rate similar to conventional therapy.
S W Wong; K W Chan; N M Paulose; H T Leong
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine     Volume:  15     ISSN:  1024-2708     ISO Abbreviation:  Hong Kong Med J     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-03     Completed Date:  2009-05-08     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  9512509     Medline TA:  Hong Kong Med J     Country:  China    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Department of Surgery, North District Hospital, Sheung Shui, Hong Kong.
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MeSH Terms
Adenoma / diagnosis
Aged, 80 and over
Carcinoma / diagnosis
Hyperparathyroidism, Primary / diagnosis*,  surgery*
Middle Aged
Neck / radionuclide imaging*,  ultrasonography*
Parathyroid Neoplasms / diagnosis
Retrospective Studies
Sensitivity and Specificity
Technetium Tc 99m Sestamibi / diagnostic use
Reg. No./Substance:
109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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