Document Detail


Scan-directed unilateral neck exploration for primary hyperparathyroidism: eight-year results from a regional hospital.
MedLine Citation:
PMID:  19342737     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the results of scan-directed unilateral neck exploration for primary hyperparathyroidism. DESIGN: Retrospective study. SETTING: Regional hospital, Hong Kong. PATIENTS: Patients who underwent parathyroid surgery for primary hyperparathyroidism between January 2000 and December 2007 were included. MAIN OUTCOME MEASURES: The demographic, imaging, biochemical, and pathological data, as well as surgical outcomes were analysed according to the treatment received. RESULTS: A total of 78 patients were included in this study; 65 underwent unilateral neck exploration with image guidance by ultrasonography or technetium Tc99m sestamibi scan. The scan sensitivity for localising the side of the lesion was 66% for ultrasound scans, 71% for technetium Tc99m sestamibi scans, and 85% for both scans used in combination. Pathological analysis showed that 95% (74/78) of the patients had a single parathyroid adenoma, two had hyperplasia of four glands, one had a double adenoma, and one a parathyroid carcinoma. Among the patients undergoing scan-directed unilateral neck exploration, one defaulted follow-up, while the remaining 64 patients achieved normal calcium levels at a median follow-up of 6 months. CONCLUSION: Scan-directed unilateral neck exploration is a safe alternative form of treatment for patients with primary hyperparathyroidism, with a cure rate similar to conventional therapy.
Authors:
S W Wong; K W Chan; N M Paulose; H T Leong
Related Documents :
10787077 - Outcome after surgery for primary hyperparathyroidism: ten-year prospective follow-up s...
13129667 - Effect of thyroid hormone supplementation on survival of euthyroid dogs with congestive...
18207127 - The use of the ligasure for hemostasis during thyroid lobectomy.
2189387 - Impact of fine needle aspiration cytology on the management of solitary thyroid nodules.
9231547 - Comparison of clinical outcome of fixed-dose subcutaneous low molecular weight heparin ...
12075727 - Tension-free vaginal tape procedure for the treatment of stress urinary incontinence: t...
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Hong Kong medical journal = Xianggang yi xue za zhi / Hong Kong Academy of Medicine     Volume:  15     ISSN:  1024-2708     ISO Abbreviation:  Hong Kong Med J     Publication Date:  2009 Apr 
Date Detail:
Created Date:  2009-04-03     Completed Date:  2009-05-08     Revised Date:  2010-03-24    
Medline Journal Info:
Nlm Unique ID:  9512509     Medline TA:  Hong Kong Med J     Country:  China    
Other Details:
Languages:  eng     Pagination:  118-21     Citation Subset:  IM    
Affiliation:
Department of Surgery, North District Hospital, Sheung Shui, Hong Kong. jeffwong@surgery.cuhk.edu.hk
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adenoma / diagnosis
Adolescent
Adult
Aged
Aged, 80 and over
Carcinoma / diagnosis
Female
Humans
Hyperparathyroidism, Primary / diagnosis*,  surgery*
Hyperplasia
Male
Middle Aged
Neck / radionuclide imaging*,  ultrasonography*
Parathyroid Neoplasms / diagnosis
Retrospective Studies
Sensitivity and Specificity
Technetium Tc 99m Sestamibi / diagnostic use
Chemical
Reg. No./Substance:
109581-73-9/Technetium Tc 99m Sestamibi

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Body fat measured by bioelectrical impedance in Hong Kong Chinese children.
Next Document:  Renal replacement therapy in critically ill patients.