| Scaling law for noise variance and spatial resolution in differential phase contrast computed tomography. | |
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MedLine Citation:
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PMID: 21452695 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: The noise variance versus spatial resolution relationship in differential phase contrast (DPC) projection imaging and computed tomography (CT) are derived and compared to conventional absorption-based x-ray projection imaging and CT. METHODS: The scaling law for DPC-CT is theoretically derived and subsequently validated with phantom results from an experimental Talbot-Lau interferometer system. RESULTS: For the DPC imaging method, the noise variance in the differential projection images follows the same inverse-square law with spatial resolution as in conventional absorption-based x-ray imaging projections. However, both in theory and experimental results, in DPC-CT the noise variance scales with spatial resolution following an inverse linear relationship with fixed slice thickness. CONCLUSIONS: The scaling law in DPC-CT implies a lesser noise, and therefore dose, penalty for moving to higher spatial resolutions when compared to conventional absorption-based CT in order to maintain the same contrast-to-noise ratio. |
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Authors:
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Guang-Hong Chen; Joseph Zambelli; Ke Li; Nicholas Bevins; Zhihua Qi |
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Publication Detail:
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Type: Letter; Research Support, N.I.H., Extramural |
Journal Detail:
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Title: Medical physics Volume: 38 ISSN: 0094-2405 ISO Abbreviation: Med Phys Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-04-01 Completed Date: 2011-04-21 Revised Date: 2012-02-01 |
Medline Journal Info:
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Nlm Unique ID: 0425746 Medline TA: Med Phys Country: United States |
Other Details:
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Languages: eng Pagination: 584-8 Citation Subset: IM |
Affiliation:
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Department of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin 53705, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Image Processing, Computer-Assisted Phantoms, Imaging Reproducibility of Results Tomography, X-Ray Computed / methods* |
| Grant Support | |
ID/Acronym/Agency:
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5T32CA009206/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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