Document Detail


Scaling characteristics of heart rate time series before the onset of ventricular tachycardia.
MedLine Citation:
PMID:  17171301     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ventricular tachycardia (VT) provokes sudden cardiac death (SCD), which is a major cause of mortality in developed countries. Implantable cardioverter-defibrillators (ICDs) are an efficient therapy for SCD prevention. In this study we analyze heart rate variability (HRV) in data stored by ICDs. In 29 patients exhibiting VT episodes, the last 1000 normal beat-to-beat intervals are analyzed and compared to an individually acquired control time series (CON). HRV analysis is performed with standard parameters of time and frequency domain as suggested by the HRV Task Force. For scaling analyses of heart rate time series, the fractal dimension is analysed, applying Higuchi's algorithm (HFD). Furthermore, detrended fluctuation analysis (DFA) is performed. None of the standard HRV parameters shows significant differences between CON and VT. Before the onset of VT, the scaling characteristics by means of HFD and DFA are significantly changed. In conclusion, scaling analysis reveals changes in autonomic heart rate modulation preceding VT.
Authors:
Mathias Baumert; Niels Wessel; Alexander Schirdewan; Andreas Voss; Derek Abbott
Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-12-14
Journal Detail:
Title:  Annals of biomedical engineering     Volume:  35     ISSN:  0090-6964     ISO Abbreviation:  Ann Biomed Eng     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-15     Completed Date:  2007-03-20     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  0361512     Medline TA:  Ann Biomed Eng     Country:  United States    
Other Details:
Languages:  eng     Pagination:  201-7     Citation Subset:  IM    
Affiliation:
Centre for Biomedical Engineering (CBME), The University of Adelaide, Adelaide, SA 5005, Australia. mathiasbaumert@web.de
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Algorithms*
Diagnosis, Computer-Assisted / methods*
Electrocardiography / methods*
Heart Failure / complications,  diagnosis*,  physiopathology*
Heart Rate*
Humans
Reproducibility of Results
Sensitivity and Specificity
Tachycardia, Ventricular / diagnosis*,  etiology,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Phonocardiographic signal analysis method using a modified hidden Markov model.
Next Document:  The impact of breathing pattern and lung size on the alcohol breath test.