Document Detail

Satoyoshi syndrome has antibody against brain and gastrointestinal tissue.
MedLine Citation:
PMID:  17405137     Owner:  NLM     Status:  MEDLINE    
Satoyoshi syndrome is a rare postnatal disorder with muscle spasms, alopecia, and diarrhea of unknown etiology. Nutritional deficiency seems to influence lifespan. We present a patient with this syndrome having a unique "mesh-like" mucosal change radiographically and white granules endoscopically in the gastrointestinal tract. A common antibody against brain, stomach, and duodenal tissue, according to Western blot analysis, was detected in the sera of two patients with this syndrome. These findings suggest that Satoyoshi syndrome is a systemic autoimmune disease involving the nervous, endocrine, and gastrointestinal systems.
Eiji Matsuura; Wataru Matsuyama; Tomoyuki Sameshima; Kimiyoshi Arimura
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Muscle & nerve     Volume:  36     ISSN:  0148-639X     ISO Abbreviation:  Muscle Nerve     Publication Date:  2007 Sep 
Date Detail:
Created Date:  2007-08-07     Completed Date:  2007-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803146     Medline TA:  Muscle Nerve     Country:  United States    
Other Details:
Languages:  eng     Pagination:  400-3     Citation Subset:  IM    
Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.
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MeSH Terms
Alopecia / diagnosis,  immunology*,  pathology
Autoantibodies / blood*
Autoimmune Diseases / diagnosis,  immunology*,  pathology
Brain / immunology
Diarrhea / diagnosis,  immunology*,  pathology
Gastric Mucosa / immunology,  pathology
Spasm / diagnosis,  immunology*
Stomach / immunology
Reg. No./Substance:

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