Document Detail


Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People.
MedLine Citation:
PMID:  20392703     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The European Working Group on Sarcopenia in Older People (EWGSOP) developed a practical clinical definition and consensus diagnostic criteria for age-related sarcopenia. EWGSOP included representatives from four participant organisations, i.e. the European Geriatric Medicine Society, the European Society for Clinical Nutrition and Metabolism, the International Association of Gerontology and Geriatrics-European Region and the International Association of Nutrition and Aging. These organisations endorsed the findings in the final document. The group met and addressed the following questions, using the medical literature to build evidence-based answers: (i) What is sarcopenia? (ii) What parameters define sarcopenia? (iii) What variables reflect these parameters, and what measurement tools and cut-off points can be used? (iv) How does sarcopenia relate to cachexia, frailty and sarcopenic obesity? For the diagnosis of sarcopenia, EWGSOP recommends using the presence of both low muscle mass + low muscle function (strength or performance). EWGSOP variously applies these characteristics to further define conceptual stages as 'presarcopenia', 'sarcopenia' and 'severe sarcopenia'. EWGSOP reviewed a wide range of tools that can be used to measure the specific variables of muscle mass, muscle strength and physical performance. Our paper summarises currently available data defining sarcopenia cut-off points by age and gender; suggests an algorithm for sarcopenia case finding in older individuals based on measurements of gait speed, grip strength and muscle mass; and presents a list of suggested primary and secondary outcome domains for research. Once an operational definition of sarcopenia is adopted and included in the mainstream of comprehensive geriatric assessment, the next steps are to define the natural course of sarcopenia and to develop and define effective treatment.
Authors:
Alfonso J Cruz-Jentoft; Jean Pierre Baeyens; Jürgen M Bauer; Yves Boirie; Tommy Cederholm; Francesco Landi; Finbarr C Martin; Jean-Pierre Michel; Yves Rolland; Stéphane M Schneider; Eva Topinková; Maurits Vandewoude; Mauro Zamboni;
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Publication Detail:
Type:  Consensus Development Conference; Journal Article; Practice Guideline; Research Support, Non-U.S. Gov't     Date:  2010-04-13
Journal Detail:
Title:  Age and ageing     Volume:  39     ISSN:  1468-2834     ISO Abbreviation:  Age Ageing     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-17     Completed Date:  2010-09-30     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  0375655     Medline TA:  Age Ageing     Country:  England    
Other Details:
Languages:  eng     Pagination:  412-23     Citation Subset:  IM    
Affiliation:
Hospital Universitario Ramón y Cajal, Madrid, Spain. acruz.hrc@salud.madrid.org <acruz.hrc@salud.madrid.org>
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Aging*
Cachexia / diagnosis
Female
Frail Elderly
Geriatric Assessment
Humans
Male
Muscle Strength*
Muscle, Skeletal / physiopathology*
Obesity / diagnosis
Sarcopenia / diagnosis*,  therapy
Comments/Corrections

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