Document Detail

Sarcomere relaxation and ischaemic myocardial injury.
MedLine Citation:
PMID:  7222468     Owner:  NLM     Status:  MEDLINE    
Material from hearts known to have had recent myocardial infarction and biopsies of dog hearts subjected to an experimental procedure producing ischaemic injury, were examined by polarising microscopy. A technique which depends on the relaxation of sarcomeres on ischaemic areas of myocardia was used and assessed for its value in the diagnosis of early myocardial infarction. We found no statistically significant difference in sarcomere lengths in ischaemic and control heart muscle in man. The dog study failed to show changes with a study period of up to 2 h after ligation. We do not support the suggestion that sarcomere length is a useful measurement in the demonstration of early myocardial ischaemic injury in man.
C L Berry; J van der Walt; R Wyse
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Virchows Archiv. A, Pathological anatomy and histology     Volume:  390     ISSN:  0340-1227     ISO Abbreviation:  Virchows Arch A Pathol Anat Histol     Publication Date:  1981  
Date Detail:
Created Date:  1981-06-25     Completed Date:  1981-06-25     Revised Date:  2008-02-20    
Medline Journal Info:
Nlm Unique ID:  7505137     Medline TA:  Virchows Arch A Pathol Anat Histol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  205-10     Citation Subset:  IM    
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MeSH Terms
Coronary Disease / pathology*
Microscopy, Electron
Myocardial Infarction / pathology*
Myocardium / ultrastructure
Myofibrils / ultrastructure*
Time Factors

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