Document Detail

Sarcomatoid carcinoma of the parotid gland with apparent metastasis of epidermoid elements to cervical lymph nodes.
MedLine Citation:
PMID:  16720456     Owner:  NLM     Status:  MEDLINE    
A case of sarcomatoid carcinoma of the parotid gland is described in a 47-year-old male. Despite radical surgery and postoperative chemoradiation therapy, a distant metastasis occurred 1 month after treatment. The primary site was composed of well-differentiated squamous cell carcinoma intermingled with spindle-shaped malignant mesenchymal cells. Immunohistochemical studies showed that keratin was present in both epithelial cells and spindle cells, whereas vimentin was present in spindle cells and absent in epithelial cells. Two lymph nodes were metastasized by the epidermoid component. The origin of the sarcomatoid component and the differential diagnosis from malignant mixed tumours are discussed.
Shiang-Fu Huang; I-How Chen; Chun-Ta Liao; Tsung-Ming Chen; Kam-Fai Lee
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta oto-laryngologica     Volume:  126     ISSN:  0001-6489     ISO Abbreviation:  Acta Otolaryngol.     Publication Date:  2006 Jun 
Date Detail:
Created Date:  2006-05-24     Completed Date:  2007-01-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370354     Medline TA:  Acta Otolaryngol     Country:  Norway    
Other Details:
Languages:  eng     Pagination:  667-71     Citation Subset:  IM    
Department of Otorhinolaryngology, Head and Neck Surgery, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan.
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MeSH Terms
Biopsy, Needle
Carcinoma, Squamous Cell / pathology*,  secondary*,  surgery
Diagnosis, Differential
Head and Neck Neoplasms / pathology,  secondary,  surgery
Lymph Nodes / pathology
Lymphatic Metastasis / pathology*
Middle Aged
Neck Dissection
Neoplasm Invasiveness
Neoplasms, Multiple Primary / diagnosis*,  pathology,  surgery
Parotid Gland / pathology,  surgery
Parotid Neoplasms / diagnosis*,  pathology,  surgery
Sarcoma / pathology,  secondary*,  surgery
Tomography, Spiral Computed

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