Document Detail

Sarcoidosis presenting with severe hypocalcaemia.
MedLine Citation:
PMID:  19184607     Owner:  NLM     Status:  In-Data-Review    
Disorders of calcium metabolism, especially hypercalcemia and hypercalceuria, are common in sarcoidosis. They are caused by extra renal unsuppressed production of 1,25 dihydroxy vitamin D at the level of the sarcoid granuloma. Hormonal changes during pregnancy have a physiological synergistic effect on this mechanism, which is primarily parathyroid hormone (PTH) dependant. However, the combination of primary hypoparathyroidism with hypocalcemia and sarcoidosis is rare. Di George syndrome, is a dysmorphic disorder characterised by aplasia/hypoplasia of thymus and parathyroid glands in addition to aortic arch anamolies and facial dysmorphia. After commencing appropriate treatment this lady made excellent recovary.
A Saeed; M Khan; S Irwin; A Fraser
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Publication Detail:
Type:  Journal Article     Date:  2009-01-31
Journal Detail:
Title:  Irish journal of medical science     Volume:  180     ISSN:  1863-4362     ISO Abbreviation:  Ir J Med Sci     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-04-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806864     Medline TA:  Ir J Med Sci     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  575-7     Citation Subset:  IM    
Department of Rheumatology, Mid Western Regional Hospital, Dooradoyle, Limerick, Ireland,
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