Document Detail


Sarcoidosis and pregnancy.
MedLine Citation:
PMID:  3627583     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sarcoidosis is usually a benign and self-limited disease, but it can occasionally be quite severe. It affects individuals most often during the reproductive years. This report reviews cases of sarcoidosis and pregnancy during a ten-year period at Downstate Medical Center. Eleven patients were stable, two experienced disease progression, and two died from complications of severe sarcoidosis. Factors indicating a poor prognosis included parenchymal lesions on chest x-ray, advanced roentgenologic staging, advanced maternal age, low inflammatory activity, requirement for drugs other than steroids, and presence of extrapulmonary sarcoidosis. Management plans are delineated for patients with advanced sarcoidosis. Some patients require evaluation before pregnancy to establish chronicity, baseline pulmonary function, inflammatory activity, roentgenographic staging, and response to treatment. Only then can the patient be given an accurate prognosis for either an uncomplicated pregnancy or one requiring intensive management by the pulmonary and perinatal teams.
Authors:
R Haynes de Regt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  70     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1987 Sep 
Date Detail:
Created Date:  1987-09-28     Completed Date:  1987-09-28     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  369-72     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Humans
Lung Diseases / epidemiology*,  mortality
New York
Pregnancy
Pregnancy Complications / epidemiology*,  mortality
Prognosis
Retrospective Studies
Sarcoidosis / epidemiology*,  mortality

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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