Document Detail

Sarcoidosis and its ophthalmic manifestations.
MedLine Citation:
PMID:  568886     Owner:  NLM     Status:  MEDLINE    
Of 532 cases of sarcoidosis in the southeastern United States, ocular manifestations were a prominent feature of the disease in 202 (38%) of the patients. Approximately one fifth of them sought medical attention because of ocular complaints. This was the second most frequent clinical manifestation, exceeded only by pulmonary symptoms. When ocular segment structures were affected, the anterior segment was involved in 171 (84.7%) of cases. Chronic granulomatous uveitis was the most common abnormality in 106 cases (52.5%). Posterior segment disease occurred in 51 (25.3%) of cases, usually in the form of chorioretinitis or preiphlebitis; it was sometimes the sole manifestation of ocular sarcoidosis, but usually accompanied abnormalities in the anterior part of the eye. The incidence of central nervous system sarcoidosis was increased when posterior segment involvement was observed. Orbital and adnexal structures, primarily lacrimal gland, were affected in 53 (27.7%) of cases.
C D Obenauf; H E Shaw; C F Sydnor; G K Klintworth
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  86     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-01-24     Completed Date:  1979-01-24     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  648-55     Citation Subset:  AIM; IM    
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MeSH Terms
Child, Preschool
Exophthalmos / complications
Eye Diseases / complications
Eye Manifestations*
Glaucoma / complications
Granuloma / complications
Infant, Newborn
Iritis / complications
Lung Diseases / complications
Middle Aged
Sarcoidosis / complications*,  diagnosis,  pathology
Uveitis / etiology*
Uveitis, Anterior / complications

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