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Sarcoidosis and Gullain-Barré syndrome.
MedLine Citation:
PMID:  21510240     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
A 35-year-old female presented with three days' history of aching discomfort in her back, chest, and ankles. She had also noticed increasing weakness of her legs and a week before admission had shown flu-like symptoms. Chest X-ray showed bilateral hilar and right paratracheal lymphadenopathy. Bronchoscopic biopsies revealed non-caseating granuloma. She was diagnosed with sarcoidosis and was given prednisolone. The patient developed facial palsy and rapidly progressive ascending paralysis beginning from the lower extremities on the third and fourth days after initial presentation, respectively. Analysis of lumbar puncture showed acellular fluid with a high protein content. EMG was consistent with diffuse sensorimotor demyelinating polyneuropathy. Thus, the diagnosis was Guillain-Barré syndrome (GBS) presenting with sarcoidosis. Intravenous immune globulin was given and prednisolone stopped. One month after initial presentation the patient was completely recovered and discharged on prednisolone therapy. If neurologic symptoms such as aching discomfort and weakness are the main complaints in patients with suspected or biopsy proven sarcoidosis, GBS should be suspected.
Authors:
Serhat Findik; Recep Bulbul; Taner Ozbenli; Esra Aslan; Ufuk Sandikci; Davut Aydin; Atilla Guven Atici; Sevket Ozkaya
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Belgica     Volume:  111     ISSN:  0300-9009     ISO Abbreviation:  Acta Neurol Belg     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-04-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0247035     Medline TA:  Acta Neurol Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  72-5     Citation Subset:  IM    
Affiliation:
Department of Pulmonary Medicine, Ondokuz Mayis University, Faculty of Medicine, Samsun, Turkey. serhatfindik1@yahoo.com
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