| Saponins in garlic as modifiers of the risk of cardiovascular disease. | |
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MedLine Citation:
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PMID: 11238805 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Most chemical and biological studies about garlic have been conducted using organosulfur compounds. However, a variety of steroid saponins from garlic and related Allium species are being increasingly recognized for their importance in biological processes. This report demonstrates the isolation and structure determination of steroid saponins from garlic and aged garlic extract (AGE). In addition, the in vitro antifungal antitumor cytotoxicity and blood coagulability effects of steroid saponins from garlic and related Allium species are provided. Animal studies on the cholesterol-lowering effects of the saponin fractions from garlic are also summarized. |
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Authors:
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H Matsuura |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: The Journal of nutrition Volume: 131 ISSN: 0022-3166 ISO Abbreviation: J. Nutr. Publication Date: 2001 Mar |
Date Detail:
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Created Date: 2001-03-12 Completed Date: 2001-04-19 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 0404243 Medline TA: J Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 1000S-5S Citation Subset: IM |
Affiliation:
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Program for Collaborative Research in the Pharmaceutical Sciences, Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, University of Illinois at Chicago, Chicago, IL 60612, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anticarcinogenic Agents / isolation & purification, therapeutic use Anticholesteremic Agents / isolation & purification, therapeutic use* Antifungal Agents / isolation & purification, therapeutic use Cardiovascular Diseases / drug therapy, prevention & control* Garlic / chemistry* Humans Magnetic Resonance Spectroscopy Plant Extracts / chemistry Plants, Medicinal* Rats Risk Factors Saponins / chemistry, isolation & purification*, pharmacology*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Anticarcinogenic Agents; 0/Anticholesteremic Agents; 0/Antifungal Agents; 0/Plant Extracts; 0/Saponins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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