Document Detail


Sampling strategies for whole genome association studies in aquaculture and outcrossing plant species.
MedLine Citation:
PMID:  19968912     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A number of farmed species are characterized by breeding populations of large full-sib families, including aquaculture species and outcrossing plant species. Whole genome association studies in such species must account for stratification arising from the full-sib family structure to avoid high rates of false discovery. Here, we demonstrate the value of selective genotyping strategies which balance the contribution of families across high and low phenotypes to greatly reduce rates of false discovery with a minimal effect on power.
Authors:
B J Hayes; I M MacLeod; M Baranski
Publication Detail:
Type:  Journal Article     Date:  2009-12-08
Journal Detail:
Title:  Genetics research     Volume:  91     ISSN:  1469-5073     ISO Abbreviation:  Genet Res (Camb)     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2010-02-03     Completed Date:  2010-05-10     Revised Date:  2010-12-28    
Medline Journal Info:
Nlm Unique ID:  101550220     Medline TA:  Genet Res (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Affiliation:
Biosciences Research Division, Department of Primary Industries, Victorian AgriBiosciences Centre, 1 Park Drive, Bundoora 3083, Australia. ben.hayes@dpi.vic.gov.au
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MeSH Terms
Descriptor/Qualifier:
Aquaculture*
Crosses, Genetic
Genome
Genome, Plant*
Genome-Wide Association Study / methods*
Genotype
Plants / genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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