| Sampling strategies for whole genome association studies in aquaculture and outcrossing plant species. | |
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MedLine Citation:
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PMID: 19968912 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A number of farmed species are characterized by breeding populations of large full-sib families, including aquaculture species and outcrossing plant species. Whole genome association studies in such species must account for stratification arising from the full-sib family structure to avoid high rates of false discovery. Here, we demonstrate the value of selective genotyping strategies which balance the contribution of families across high and low phenotypes to greatly reduce rates of false discovery with a minimal effect on power. |
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Authors:
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B J Hayes; I M MacLeod; M Baranski |
Publication Detail:
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Type: Journal Article Date: 2009-12-08 |
Journal Detail:
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Title: Genetics research Volume: 91 ISSN: 1469-5073 ISO Abbreviation: Genet Res (Camb) Publication Date: 2009 Dec |
Date Detail:
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Created Date: 2010-02-03 Completed Date: 2010-05-10 Revised Date: 2010-12-28 |
Medline Journal Info:
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Nlm Unique ID: 101550220 Medline TA: Genet Res (Camb) Country: England |
Other Details:
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Languages: eng Pagination: 367-71 Citation Subset: IM |
Affiliation:
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Biosciences Research Division, Department of Primary Industries, Victorian AgriBiosciences Centre, 1 Park Drive, Bundoora 3083, Australia. ben.hayes@dpi.vic.gov.au |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aquaculture* Crosses, Genetic Genome Genome, Plant* Genome-Wide Association Study / methods* Genotype Plants / genetics* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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