| Sample size for a dose-response study. | |
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MedLine Citation:
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PMID: 1300202 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This paper deals with a method of sample size allocation for a dose-response study assuming a logistic model for the dose-response curve. The method is based on the precision with which one wishes to estimate the dose that would produce the efficacy resulting in a clinically important difference from a placebo. An example is given to illustrate the methodology. The main development of the paper is for a binary response and is suitably modified for a continuous variable. |
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Authors:
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H I Patel |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Journal of biopharmaceutical statistics Volume: 2 ISSN: 1054-3406 ISO Abbreviation: J Biopharm Stat Publication Date: 1992 |
Date Detail:
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Created Date: 1993-05-26 Completed Date: 1993-05-26 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9200436 Medline TA: J Biopharm Stat Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1-8 Citation Subset: IM |
Affiliation:
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Berlex Laboratories, Inc., Wayne, New Jersey 07470. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Dose-Response Relationship, Drug* Humans Models, Statistical* Research Design / statistics & numerical data* |
| Comments/Corrections | |
Erratum In:
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J Biopharm Stat 1994 Mar;4(1):127 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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