Document Detail

Salt restriction for the prevention of cardiovascular disease.
MedLine Citation:
PMID:  20644699     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Restricting the dietary intake of sodium chloride is associated with a reduction of the arterial blood pressure by approximately 4/2 mm Hg in hypertensive patients and by approximately 1/0.6 mm Hg in normotensive persons. As the cardiovascular risk is known to rise steadily with systolic blood pressure values starting from 115 mm Hg, lowering the mean blood pressure of the general population by dietary salt restriction would seem to be a practicable form of primary prevention of cardiovascular disease.
METHOD: Selective literature search and review.
RESULTS: Multiple studies have shown dietary salt restriction to be associated with lower cardiovascular morbidity and mortality. The reduction of adjusted relative risk in controlled observational studies ranges from 25% over 15 years to 41% over three years.
CONCLUSION: On the basis of the available studies, it seems likely that a moderate lowering of the daily intake of sodium chloride by the general population from 8 to 12 grams per day (the current value) to 5 to 6 grams per day would be a useful public health measure, with economic benefits as well. The potential risks for certain groups of individuals are foreseeable and controllable. A general reduction of dietary salt intake can only be achieved by reducing the sodium chloride content of industrially processed foods, as these account for 75% to 80% of the sodium chloride consumed daily. Aside from a general reduction of dietary salt intake, further important primary prevention measures for the general population include changes in lifestyle and in dietary habits.
Dieter Klaus; Joachim Hoyer; Martin Middeke
Related Documents :
19669669 - Pro-inflammatory cytokines of rat vasculature in doca-salt treatment.
10433039 - Inflammation of the cardiac conduction system in a case of hyperthyroidism.
11040249 - Proximal sodium reabsorption: an independent determinant of blood pressure response to ...
8478039 - Pressor reactivity to norepinephrine and angiotensin in salt-sensitive hypertensive pat...
22672089 - Prehypertension in adolescents: risk and progression.
18573249 - Lack of the serotonin transporter does not prevent mineralocorticoid hypertension in ra...
24219389 - Evaluation of carotid intima-media thickness and aortic elasticity in patients with non...
3361579 - Antihypertensive thiadiazoles. 2. vasodilator activity of some 2-aryl-5-guanidino-1,3,4...
2681589 - The microcirculation in hypertension.
Publication Detail:
Type:  Journal Article; Review     Date:  2010-07-02
Journal Detail:
Title:  Deutsches Ärzteblatt international     Volume:  107     ISSN:  1866-0452     ISO Abbreviation:  Dtsch Arztebl Int     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-07-20     Completed Date:  2010-12-02     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101475967     Medline TA:  Dtsch Arztebl Int     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  457-62     Citation Subset:  IM    
Medizinische Klinik des Klinikums Dortmund, Quellenweg 7, Dortmund,
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Cardiovascular Diseases / diet therapy*,  mortality*
Diet, Sodium-Restricted / utilization*
Risk Assessment
Risk Factors
Survival Analysis
Survival Rate
Treatment Outcome
Comment In:
Dtsch Arztebl Int. 2010 Nov;107(47):843; author reply 843   [PMID:  21173904 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Obesity prevalence in Nepal: public health challenges in a low-income nation during an alarming worl...
Next Document:  Trauma care in Germany: major differences in case fatality rates between centers.