| Salt induces biosynthesis of hemolytically active compounds in the xerotolerant food-borne fungus Wallemia sebi. | |
| | |
MedLine Citation:
|
PMID: 22092533 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Wallemia sebi is a xerotolerant, ubiquitous, food-borne, mycotoxigenic fungus. An ethanol extract of its mycelium demonstrated a strong hemolytic activity, which was further enhanced at high salt concentrations in the growth medium. Characterization of the extract using gas chromatography-mass spectrometry revealed a mixture of sterols and unsaturated fatty acids, indicating the latter as responsible for the hemolytic activity. The lytic activity of the extract is here studied using red blood cells and artificial small lipid vesicles with various lipid compositions. This shows concentration-dependent hemolysis and preferential activity toward lipid membranes with greater fluidity. The W. sebi lytic activity on mammalian erythrocytes shows its potential involvement in the formation of lesions in subcutaneous infections, in farmer's lung disease, and in consumption of food and feed that are contaminated with food-borne W. sebi. |
| | |
Authors:
|
Tanja Botić; Marjetka K Kunčič; Kristina Sepčić; Zeljko Knez; Nina Gunde-Cimerman |
Related Documents
:
|
12489393 - Spatial and temporal distribution of larvae and juveniles of hoplias aff. malabaricus (... 16506563 - Food of larval anopheles culicifacies and anopheles varuna in a stream habitat in sri l... 22591343 - Distinctive exotic flavor and aroma compounds of some exotic tropical fruits and berrie... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-10-6 |
Journal Detail:
|
Title: FEMS microbiology letters Volume: - ISSN: 1574-6968 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-11-18 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7705721 Medline TA: FEMS Microbiol Lett Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
© 2011 Federation of European Microbiological Societies. Published by Blackwell Publishing Ltd. All rights reserved. |
Affiliation:
|
Laboratory for Separation Processes and Product Design, Faculty for Chemistry and Chemical Engineering, University of Maribor, Maribor, Slovenia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Analysis of human perception of facial skin radiance by means of image histogram parameters of surfa...
Next Document: Reducing errors benefits the field-based learning of a fundamental movement skill in children.