Document Detail


Salivary levels of Tumour Necrosis Factor-alpha in patients with recurrent aphthous stomatitis.
MedLine Citation:
PMID:  20711148     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
STUDY DESIGN: The study group was composed of 20 patients previously diagnosed with RAS and randomly selected. As a control group 10 healthy patients were also randomly selected. In both groups a TNFα assessment was carried out in non stimulated saliva. All the patients in the study group presented active lesions at the moment of the salivary sample collection. Values oscillating between 0 and 8.1 pg/ml were considered as normal.
RESULTS: Salivary TNFα levels are 2 to 5 times higher in RAS patients than those of healthy patients.
CONCLUSIONS: TNFα has a possible implication in the RAS etiology and it may also have an important role in the search of new treatments for this disease.
Authors:
Asier Eguia-del Valle; Rafael Martinez-Conde-Llamosas; Jose López-Vicente; Agurne Uribarri-Etxebarria; José-Manuel Aguirre-Urizar
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Publication Detail:
Type:  Journal Article     Date:  2011-01-01
Journal Detail:
Title:  Medicina oral, patología oral y cirugía bucal     Volume:  16     ISSN:  1698-6946     ISO Abbreviation:  Med Oral Patol Oral Cir Bucal     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101231694     Medline TA:  Med Oral Patol Oral Cir Bucal     Country:  Spain    
Other Details:
Languages:  eng     Pagination:  e33-6     Citation Subset:  D; IM    
Affiliation:
Oral Medicine, Faculty of Medicine and Dentistry, University of the Basque Country, Spain. aeguiadelvalle@yahoo.es
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