Document Detail


Salivary gland scintigraphy with 99mTc-pertechnetate in Sjögren's syndrome: relationship to clinicopathologic features of salivary and lacrimal glands.
MedLine Citation:
PMID:  9021552     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Salivary gland scintigraphy was performed on 52 patients who were suspected of having Sjögren's syndrome (SS), and the results were compared with clinicopathologic features of the salivary and lacrimal glands. The time-activity curves which were obtained from computer-assisted analysis of 99mTc-pertechnetate (99mTc) scintigraphy were classified into four types (normal, median, flat and sloped types). The stimulated parotid flow rate decreased and the incidence of SS-related sialographic and histopathologic findings increased significantly as the scintigraphic abnormality advanced. In addition, the lacrimal gland function decreased and the proportion of patients diagnosed as having keratoconjunctivitis sicca (KCS) increased significantly as the scintigraphic abnormality advanced. These results indicate that the results of scintigraphy are related not only to the clinicopathologic features of the salivary glands but also to the lacrimal gland function in SS.
Authors:
T Saito; H Fukuda; M Horikawa; K Ohmori; M Shindoh; A Amemiya
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology     Volume:  26     ISSN:  0904-2512     ISO Abbreviation:  J. Oral Pathol. Med.     Publication Date:  1997 Jan 
Date Detail:
Created Date:  1997-03-31     Completed Date:  1997-03-31     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8911934     Medline TA:  J Oral Pathol Med     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  46-50     Citation Subset:  D; IM    
Affiliation:
First Department of Oral Surgery, Hokkaido University School of Dentistry, Sapporo, Japan.
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MeSH Terms
Descriptor/Qualifier:
Chi-Square Distribution
Disease Progression
Female
Humans
Keratoconjunctivitis Sicca / etiology,  physiopathology*
Lacrimal Apparatus / pathology,  physiopathology*
Male
Saliva / secretion
Salivary Glands / pathology,  physiopathology,  radionuclide imaging*
Secretory Rate
Sialography
Sjogren's Syndrome / complications,  physiopathology,  radionuclide imaging*
Sodium Pertechnetate Tc 99m / diagnostic use
Statistics, Nonparametric
Xerostomia / etiology,  physiopathology
Chemical
Reg. No./Substance:
23288-60-0/Sodium Pertechnetate Tc 99m

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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