Document Detail

Salivary free insulin-like growth factor-i levels: effects of an acute physical exercise in athletes.
MedLine Citation:
PMID:  19337006     Owner:  NLM     Status:  MEDLINE    
BACKGROUND/AIMS: The offer of human saliva IGF-I (sIGF-I) measurement in athletes investigation is a new proposal. The aim was to investigate the physical exercise effect on sIGF-I and explore plasma free IGF-I relation. MATERIALS AND METHODS: Saliva and blood were collected from well-trained athletes, investigated immediately before and at the end of a physical exercise test. RESULTS: sIGF-I was significantly increased at the end of the physical exercise. The plasma free IGF-I concentrations did not demonstrate any difference. The saliva total protein level (sTP) was also significantly increased. A positive correlation between sTP and sIGF-I, was observed, both before and after physical exercise, and between salivary and plasma free IGF-I only after physical exercise. The salivary free IGF-I level significantly increased after physical exercise, moreover a correlation with the plasma levels exists in post-exercise condition. CONCLUSION: The physical exercise affects sIGF-I as well as the sTP. The correlation between plasma and salivary free IGF-I levels only in post-exercise condition suggests further studies to investigate the effects of different type and duration of physical exercise. The comparison with other salivary biochemical parameter investigation would also further increase comprehension on the role of salivary IGF-I.
G Antonelli; R Gatti; M Prearo; E F De Palo
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of endocrinological investigation     Volume:  32     ISSN:  1720-8386     ISO Abbreviation:  J. Endocrinol. Invest.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-04-01     Completed Date:  2009-07-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7806594     Medline TA:  J Endocrinol Invest     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  1-5     Citation Subset:  IM    
Section of Clinical Biochemistry, Department of Medical Diagnostic Sciences and Sp. Ther, University of Padua, 35121 Padua, Italy.
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MeSH Terms
Insulin-Like Growth Factor I / metabolism*
Physical Exertion*
Saliva / metabolism*
Salivary Proteins and Peptides / metabolism
Young Adult
Reg. No./Substance:
0/Salivary Proteins and Peptides; 67763-96-6/Insulin-Like Growth Factor I

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