| Saline-resistant metabolic alkalosis, severe hypokalemia and hypertension in a 74-year-old woman. | |
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MedLine Citation:
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PMID: 10661485 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The case of a 74-year-old woman with past history of hypertension and cerebrovascular accident admitted with pneumonia, dehydration, hypernatremia and severe hypokalemic alkalosis is presented. After correction of the hypertonic dehydration, the hypokalemia and alkalosis persisted in spite of aggressive potassium supplementation and the patient became hypertensive. Mineralocorticoid excess was suspected and excluded after extensive endocrinological testing. The use of aldactone failed to revert the abnormalities. Triamterene administration corrected the electrolytes and acid base aberrations, and dramatically improved the blood pressure control. This clinical picture is compatible with the diagnosis of Liddle's syndrome. Our patient exemplifies the unique occurrence of hypokalemic metabolic alkalosis in association with volume contraction at the start of the hospitalization and volume expansion later on her course. |
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Authors:
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L Rezkalla; S Borra |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical nephrology Volume: 53 ISSN: 0301-0430 ISO Abbreviation: Clin. Nephrol. Publication Date: 2000 Jan |
Date Detail:
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Created Date: 2000-02-18 Completed Date: 2000-02-18 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0364441 Medline TA: Clin Nephrol Country: GERMANY |
Other Details:
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Languages: eng Pagination: 66-70 Citation Subset: IM |
Affiliation:
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Department of Medicine, Kingsbrook Jewish Medical Center, Brooklyn, NY 11203, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Alkalosis / complications*, drug therapy, metabolism Diuretics / therapeutic use* Female Humans Hypertension / complications, drug therapy Hypokalemia / complications*, drug therapy, metabolism Triamterene / therapeutic use* |
| Chemical | |
Reg. No./Substance:
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0/Diuretics; 396-01-0/Triamterene |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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