Document Detail


Salicylic acid differentially affects suspension cell cultures of Lotus japonicus and one of its non-symbiotic mutants.
MedLine Citation:
PMID:  20012170     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Salicylic acid (SA) is known to play an important role in the interaction between plant and micro-organisms, both symbiotic and pathogen. In particular, high levels of SA block nodule formation and mycorrhizal colonization in plants. A mutant of Lotus japonicus, named Ljsym4-2, was characterized as unable to establish positive interactions with Rhizobium and fungi (NOD(-), MYC(-)); in particular, it does not recognize signal molecules released by symbiotic micro-organisms so that eventually, epidermal cells undergo PCD at the contact area. We performed a detailed characterization of wild-type and Ljsym4-2 cultured cells by taking into account several parameters characterizing cell responses to SA, a molecule strongly involved in defense signaling pathways. In the presence of 0.5 mM SA, Ljsym4-2 suspension-cultured cells reduce their growth and eventually die, whereas in order to induce the same effects in wt suspension cells, SA concentration must be raised to 1.5 mM. An early and short production of nitric oxide (NO) and reactive oxygen species (ROS) was detected in wt-treated cells. In contrast, a continuous production of NO and a double-peak ROS response, similar to that reported after a pathogenic attack, was observed in the mutant Ljsym4-2 cells. At the molecular level, a constitutive higher level of a SA-inducible pathogenesis related gene was observed. The analysis in planta revealed a strong induction of the LjPR1 gene in the Ljsym4-2 mutant inoculated with Mesorhizobium loti.
Authors:
Fiorenza Bastianelli; Alex Costa; Marco Vescovi; Enrica D'Apuzzo; Michela Zottini; Maurizio Chiurazzi; Fiorella Lo Schiavo
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-12-10
Journal Detail:
Title:  Plant molecular biology     Volume:  72     ISSN:  1573-5028     ISO Abbreviation:  Plant Mol. Biol.     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-02-04     Completed Date:  2010-03-01     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9106343     Medline TA:  Plant Mol Biol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  469-83     Citation Subset:  IM    
Affiliation:
Department of Biology, Padova University, Via U. Bassi 58/B, 35131 Padua, Italy.
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MeSH Terms
Descriptor/Qualifier:
Apoptosis / drug effects
Base Sequence
Cell Proliferation / drug effects
Cells, Cultured
DNA Primers / genetics
DNA, Plant / genetics
Genes, Plant
Lotus / drug effects*,  genetics,  metabolism,  microbiology
Mutation
Nitric Oxide / metabolism
Reactive Oxygen Species / metabolism
Rhizobium / physiology
Salicylic Acid / metabolism,  pharmacology*
Signal Transduction / drug effects
Symbiosis / genetics,  physiology
Chemical
Reg. No./Substance:
0/DNA Primers; 0/DNA, Plant; 0/Reactive Oxygen Species; 10102-43-9/Nitric Oxide; 69-72-7/Salicylic Acid

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