Document Detail

Salicylates in the treatment of arthritic disease. How safe and effective?
MedLine Citation:
PMID:  3054846     Owner:  NLM     Status:  MEDLINE    
Despite the adverse effects of aspirin, many physicians still consider it to be the drug of choice for initial treatment of arthritic disorders. Nonsteroidal antiinflammatory drugs (NSAIDs) are better tolerated than aspirin but have similar, although milder, side effects. The nonacetylated salicylates appear to have fewer adverse effects than either aspirin or the NSAIDs and therefore may warrant greater consideration as first-line therapy for arthritis.
R D Altman
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Postgraduate medicine     Volume:  84     ISSN:  0032-5481     ISO Abbreviation:  Postgrad Med     Publication Date:  1988 Nov 
Date Detail:
Created Date:  1988-12-01     Completed Date:  1988-12-01     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  0401147     Medline TA:  Postgrad Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  206-10     Citation Subset:  AIM; IM    
Department of Medicine, University of Miami School of Medicine, FL 33101.
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MeSH Terms
Anti-Inflammatory Agents, Non-Steroidal / adverse effects,  pharmacology,  therapeutic use
Arthritis / drug therapy*
Aspirin / therapeutic use
Cell Aggregation / drug effects
Gastrointestinal Diseases / chemically induced
Neutrophils / drug effects
Prostaglandins / biosynthesis
Salicylates / adverse effects,  pharmacology,  therapeutic use*
Reg. No./Substance:
0/Anti-Inflammatory Agents, Non-Steroidal; 0/Prostaglandins; 0/Salicylates; 50-78-2/Aspirin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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