Document Detail

Salbutamol by pressure-packed aerosol and by intermittent positive pressure ventilation in chronic obstructive bronchitis.
MedLine Citation:
PMID:  348225     Owner:  NLM     Status:  MEDLINE    
The forced expiratory volume in one second (FEV1) response to salbutamol administered by pressure-packed aerosol 200 microgram, and intermittent positive pressure ventilation (IPPV), 5 and 10 mg, was determined in 60 patients with chronic bronchitis with airway obstruction. The bronchodilator response to salbutamol by IPPV was greater than by pressure-packed aerosol only in patients with severe airways obstruction and little additional benefit was gained with the 10 mg dose.
N Berend; J Webster; G E Marlin
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  British journal of diseases of the chest     Volume:  72     ISSN:  0007-0971     ISO Abbreviation:  Br J Dis Chest     Publication Date:  1978 Apr 
Date Detail:
Created Date:  1978-07-15     Completed Date:  1978-07-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7511123     Medline TA:  Br J Dis Chest     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  122-4     Citation Subset:  IM    
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MeSH Terms
Airway Obstruction / drug therapy*
Albuterol / administration & dosage*,  therapeutic use
Bronchitis / drug therapy*
Chronic Disease
Clinical Trials as Topic
Double-Blind Method
Forced Expiratory Volume
Intermittent Positive-Pressure Breathing*
Middle Aged
Positive-Pressure Respiration*
Reg. No./Substance:
0/Aerosols; 18559-94-9/Albuterol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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