Document Detail


Sake Lees Fermented with Lactic Acid Bacteria Prevents Allergic Rhinitis-Like Symptoms and IgE-Mediated Basophil Degranulation.
MedLine Citation:
PMID:  21228477     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
We tested the effect of oral administration of fermented sake lees with lactic acid bacteria (FESLAB) on a murine model of allergic rhinitis upon immunization and nasal sensitization with ovalbumin (OVA). We used Lactobacillus paracasei NPSRIk-4 (isolated from sake lees), and L. brevis NPSRIv-8 (from fermented milk) as starter strains to produce the FESLAB. Oral FESLAB administration resulted in the development of significantly fewer sneezing symptoms than those seen in sham control animals given sterile water. We also found that FESLAB suppressed the allergen-induced degranulation of RBL2H3 rat basophilic leukemia cells.
Authors:
Seiji Kawamoto; Mitsuoki Kaneoke; Kayo Ohkouchi; Yuichi Amano; Yuki Takaoka; Kazunori Kume; Tsunehiro Aki; Susumu Yamashita; Ken-Ichi Watanabe; Motoni Kadowaki; Dai Hirata; Kazuhisa Ono
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Publication Detail:
Type:  Journal Article     Date:  2011-01-07
Journal Detail:
Title:  Bioscience, biotechnology, and biochemistry     Volume:  75     ISSN:  1347-6947     ISO Abbreviation:  Biosci. Biotechnol. Biochem.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-01-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205717     Medline TA:  Biosci Biotechnol Biochem     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  140-4     Citation Subset:  IM    
Affiliation:
Department of Molecular Biotechnology, Graduate School of Advanced Sciences of Matter, Hiroshima University.
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