Document Detail


Safety and use of autologous blood donation during the third trimester of pregnancy.
MedLine Citation:
PMID:  2735369     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To examine autologous blood donation during the third trimester of pregnancy, records of 272 blood donors who donated by standard procedures were reviewed. The incidence of vasovagal reactions at autologous donation was 2.1% (7/341) versus 1.1% (1370/121,539) at homologous donation (p = 0.17). Follow-up was available for 199 of these donors and 10 additional donors with fetal monitoring. Infant morbidity and mortality rates were not higher than expected; 0.5% (1/214) was stillborn. Although 11% (24/209) of deliveries was associated with autologous transfusion, only 4.3% (9/209) would have had a hemoglobin level less than 8 gm/dl without transfusion. Patients with placenta previa had the highest incidence of transfusion, 83% (5/6). Transfusion incidence was higher for women donating within 1 week of delivery, 21% (8/38), versus 9.4% (16/171) for women donating earlier in pregnancy (p = 0.044). We recommend that donation be completed by 2 weeks before the estimated date of confinement to allow for recovery of red cell mass.
Authors:
P A McVay; R W Hoag; M S Hoag; P T Toy
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  160     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1989 Jun 
Date Detail:
Created Date:  1989-07-20     Completed Date:  1989-07-20     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1479-86; discussion 1486-8     Citation Subset:  AIM; IM    
Affiliation:
Department of Laboratory Medicine, University of California, San Francisco.
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MeSH Terms
Descriptor/Qualifier:
Adult
Blood Donors*
Blood Transfusion, Autologous* / adverse effects
Cesarean Section
Delivery, Obstetric
Female
Fetal Monitoring
Follow-Up Studies
Humans
Infant, Newborn
Obstetric Labor Complications
Pregnancy
Pregnancy Trimester, Third*
Grant Support
ID/Acronym/Agency:
KO7 HLO1270/HL/NHLBI NIH HHS; R01 HL 36715/HL/NHLBI NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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