Document Detail

Safety of specific immunotherapy: a retrospective study.
MedLine Citation:
PMID:  7874322     Owner:  NLM     Status:  MEDLINE    
A large experience in specific immunotherapy is reviewed in order to assess the safety of this treatment. From 1968 through September 30, 1993, 300,086 injections were administered to 6,319 patients suffering from allergic asthma and/or rhinitis. Systemic reactions reported during the whole period were 184 (0.061%) in 134 subjects (2.1%) and consisted of: urticaria (59.3%), mild asthmatic attacks (23.9%), asthma and urticaria (9.7%), and spasmodic rhinitis (7.1%). The absence of cases of anaphylaxis confirms the safety of specific immunotherapy. This kind of treatment should be considered as first-line therapy, if carried out in a specialized setting.
A Luigi; G Senna; P Mezzelani; G Pappalardo
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of investigational allergology & clinical immunology     Volume:  4     ISSN:  1018-9068     ISO Abbreviation:  J Investig Allergol Clin Immunol     Publication Date:    1994 Sep-Oct
Date Detail:
Created Date:  1995-04-05     Completed Date:  1995-04-05     Revised Date:  2013-07-31    
Medline Journal Info:
Nlm Unique ID:  9107858     Medline TA:  J Investig Allergol Clin Immunol     Country:  SPAIN    
Other Details:
Languages:  eng     Pagination:  250-4     Citation Subset:  IM    
Allergy Department of Verona General Hospital, Italy.
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MeSH Terms
Asthma / therapy
Desensitization, Immunologic / adverse effects*
Respiratory Hypersensitivity / therapy*
Retrospective Studies
Rhinitis / therapy

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