| Safety in the Use of Dexmedetomidine (Precedex) for Deep Brain Stimulation Surgery: Our Experience in 23 Randomized Patients. | |
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MedLine Citation:
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PMID: 22780449 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Objective: Evaluation of safety and efficacy of dexmedetomidine in deep brain stimulation (DBS) surgery. Materials and Methods: A cohort of 23 patients, candidates for DBS for Parkinson's disease, Tourette syndrome, or obsessive-compulsive disorder, was randomized in two groups: dexmedetomidine group and control group. Standard anesthesiologic parameters were recorded and analyzed, together with the need for other medications. A ten-degree scale (visual analog scale) assessing patient discomfort during DBS also was recorded at the end of surgery. Results: The results demonstrated good stability of intraoperative monitoring: no respiratory depression and good overall cooperation with the neurologist, while no side-effects were recorded. Conclusions: Our conclusion is that dexmedetomidine should be considered as a valuable option for sedation in poorly collaborating patients undergoing DBS surgery. |
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Authors:
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Marco Sassi; Edvin Zekaj; Alessandra Grotta; Alberto Pollini; Armando Pellanda; Massimo Borroni; Claudio Pacchetti; Claudia Menghetti; Mauro Porta; Domenico Servello |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-7-10 |
Journal Detail:
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Title: Neuromodulation : journal of the International Neuromodulation Society Volume: - ISSN: 1525-1403 ISO Abbreviation: - Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-7-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9804159 Medline TA: Neuromodulation Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 International Neuromodulation Society. |
Affiliation:
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Functional Neurosurgical Unit, IRCCS Galeazzi, Milan, Italy; Department of Statistics, University of Milano-Bicocca, Milan, Italy; and Department of Neurology, IRCCS C. Mondino Institute of Neurology Foundation, University of Pavia, Pavia, Italy. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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