Document Detail


Safety and immunogenicity of Salmonella typhi Ty21a vaccine in young Thai children.
MedLine Citation:
PMID:  8432597     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Salmonella typhi Ty21a vaccine in a liquid formulation was evaluated in 634 Thai children 2 to 6 years of age. The seroconversion rate was 69% for those who received vaccine versus 14% for those who received placebo (P < 0.005). The immune responses among vaccine recipients ranged from 60% in 3-year-olds to 81% for 6-year-olds.
Authors:
S J Cryz; N Vanprapar; U Thisyakorn; T Olanratmanee; G Losonsky; M M Levine; S Chearskul
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Infection and immunity     Volume:  61     ISSN:  0019-9567     ISO Abbreviation:  Infect. Immun.     Publication Date:  1993 Mar 
Date Detail:
Created Date:  1993-03-18     Completed Date:  1993-03-18     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0246127     Medline TA:  Infect Immun     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1149-51     Citation Subset:  IM    
Affiliation:
Swiss Serum and Vaccine Institute, Berne.
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MeSH Terms
Descriptor/Qualifier:
Age Factors
Antibodies, Bacterial / biosynthesis
Child, Preschool
Humans
Immunoglobulin G / immunology
Lipopolysaccharides / immunology
Salmonella typhi / immunology*
Thailand
Typhoid Fever / prevention & control
Typhoid-Paratyphoid Vaccines / immunology*,  standards
Vaccination
Chemical
Reg. No./Substance:
0/Antibodies, Bacterial; 0/Immunoglobulin G; 0/Lipopolysaccharides; 0/Typhoid-Paratyphoid Vaccines
Comments/Corrections

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