Document Detail


Safety and efficacy of programming a high number of antitachycardia pacing attempts for fast ventricular tachycardia: a prospective study.
MedLine Citation:
PMID:  22547765     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIMS: Little is known about the optimal number of antitachycardia pacing (ATP) attempts to programme in the fast ventricular tachycardia (FVT) zone. We sought to analyse the long-term efficacy and safety of programming a high number of ATP attempts for FVTs.METHODS AND RESULTS: All patients receiving an implantable cardioverter/defibrillator (ICD) for coronary artery disease or dilated cardiomyopathy for primary and secondary prevention between 2000 and 2009 were prospectively included. Implantable cardioverter/defibrillators were programmed to deliver 10 ATP attempts for FVT cycle lengths (CLs) of 250-300 ms (200-240 b.p.m.) before shock delivery (5 bursts, then 5 ramps; 8-10 extrastimuli at 81-88% FVT CL; minimal pacing CL 180 ms). Among 770 patients included and followed for 40.6 ± 25.6 months, 137 (17.8%) experienced a total of 1839 FVTs, 1713 of which were ATP-terminated (unadjusted efficacy = 93.1%, adjusted = 81.7%), 106 ATP-accelerated (5.8%), and 20 ATP-resistant (1.1%). The majority of FVT episodes were successfully treated by one or two attempts (98.3%). However, patient-based analysis showed that 17 (12.4%), 8 (5.8%), and 5 patients (2.1%) had at least one episode treated by three or more, four or more, and five or more ATP attempts. The benefit of this strategy was reduced after five attempts. The majority of FVT episodes was asymptomatic and diagnosed at device interrogation during follow-up: syncope and pre-syncope occurred in only 0.2 and 0.4% of episodes, respectively.CONCLUSION: Programming a high number of ATP attempts (up to five ATP attempts) in the FVT zone is both safe and efficient and could prevent shocks in numerous ICD recipients.
Authors:
Raphaël P Martins; Hugues Blangy; Lucian Muresan; Luc Freysz; Laurent Groben; Pierre-Yves Zinzius; Jérôme Schwartz; Jean-Marc Sellal; Etienne Aliot; Nicolas Sadoul
Related Documents :
19046065 - Severity of gentamicin's nephrotoxic effect on patients with infective endocarditis: a ...
20922415 - Clinical efficacy of saccharomyces boulardii or metronidazole in symptomatic children w...
2803775 - Topical antibiotic prophylaxis for cataract surgery: a controlled trial of fusidic acid...
21801115 - Combined use of botulinum toxin type a and b for forehead rhytides: a randomized, doubl...
24442385 - Carpal tunnel release in patients with diabetes result in poorer outcome in long-term s...
20188265 - Reversed shoulder arthroplasty with modified l'episcopo for combined loss of active ele...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-29
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  -     ISSN:  1532-2092     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-5-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
CHU Nancy, Service de Cardiologie, 54511 Vandoeuvre les Nancy, France.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Primary hyperoxaluria Type 1: indications for screening and guidance for diagnosis and treatment.
Next Document:  Long-term follow-up after cryoablation for adolescent atrioventricular nodal reentrant tachycardia: ...