| Safety and efficacy of preoperative portal vein embolization with polyvinyl alcohol in 58 patients with liver metastases. | |
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MedLine Citation:
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PMID: 16304024 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: The objective of our study was to evaluate the safety and efficacy of transhepatic lobar portal vein embolization (PVE) using polyvinyl alcohol (PVA) particles to induce contralateral lobar hypertrophy in patients with liver-only metastases and normal underlying liver function. MATERIALS AND METHODS: Fifty-eight consecutive patients with small predicted future liver remnants (FLRs) underwent PVE with PVA particles to induce hypertrophy of the contralateral hemi-liver before surgical resection of liver metastases. Total liver, right hemi-liver, and left hemi-liver volumes were calculated before and after embolization using a 3D workstation. RESULTS: Eight patients underwent left PVE; 47, right PVE; and three, right and segment IV PVE. There were no major complications of the procedure. The mean increases in the ratio of the FLR to the total estimated liver volume after right, right and segment IV, and left PVE were 9%, 10%, and 3%, respectively; the corresponding mean hypertrophy ratios were 24.3%, 31.9%, and 1.5%, respectively. CONCLUSION: Right PVE using PVA particles alone as the embolic agent is safe and effective in achieving left hemi-liver hypertrophy. In contrast, left PVE did not induce significant right hemi-liver hypertrophy in this patient population. |
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Authors:
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Anne M Covey; Scott Tuorto; Lynn A Brody; Constantinos T Sofocleous; Johanna Schubert; Hendrik von Tengg-Kobligk; George I Getrajdman; Lawrence H Schwartz; Yuman Fong; Karen T Brown |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: AJR. American journal of roentgenology Volume: 185 ISSN: 0361-803X ISO Abbreviation: AJR Am J Roentgenol Publication Date: 2005 Dec |
Date Detail:
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Created Date: 2005-11-23 Completed Date: 2006-01-27 Revised Date: 2008-02-15 |
Medline Journal Info:
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Nlm Unique ID: 7708173 Medline TA: AJR Am J Roentgenol Country: United States |
Other Details:
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Languages: eng Pagination: 1620-6 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA. coveya@mskcc.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Aged, 80 and over Embolization, Therapeutic / methods* Female Humans Imaging, Three-Dimensional Liver Function Tests Liver Neoplasms / radiography, secondary, therapy* Male Middle Aged Phlebography Polyvinyl Alcohol / therapeutic use* Portal Vein* Preoperative Care Radiography, Interventional Retrospective Studies Tomography, X-Ray Computed Treatment Outcome |
| Chemical | |
Reg. No./Substance:
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9002-89-5/Polyvinyl Alcohol |
| Comments/Corrections | |
Comment In:
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AJR Am J Roentgenol. 2006 Jul;187(1):W125; author reply 126
[PMID:
16794127
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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