Document Detail

Safety and efficacy of exercise training in patients with an idiopathic inflammatory myopathy--a systematic review.
MedLine Citation:
PMID:  21890619     Owner:  NLM     Status:  Publisher    
Objective. Idiopathic inflammatory myopathies (IIMs) are a group of rare heterogeneous autoimmune skeletal muscle disorders characterized by muscle weakness, excessive muscle fatigue and diminished aerobic fitness. Exercise training could be one way to prevent or delay the negative effects of the disease and the impairments seen in patients with an IIM. The objective was to examine whether exercise training is safe and effective in patients with an IIM.Methods. All experimental studies that assessed the safety and/or efficacy of an exercise training programme in patients with an IIM except for case studies were reviewed. Pre-MEDLINE, MEDLINE and EMBASE database searching was done up to November 2010. Information was extracted on the number of participants, characteristics of participants, type of intervention, type of outcome measure, type of study design, report characteristics, geographical origin and risk of bias within studies. The change (percentage and significance) in group mean or median for each outcome measure in each study was determined as well.Results. Two randomized controlled trials, one non-randomized controlled trial and nine uncontrolled trials were included. No studies in children were found. Safety measures did not worsen and efficacy measures improved or did not change. Most of the included studies had a high selection and/or allocation bias.Conclusions. In conclusion, it appears that exercise training is safe and effective in adult patients with active as well as inactive stable IIMs. However, more studies with a well-controlled design are needed. In addition, studies in children with an IIM are indicated.
Gerarda E A Habers; Tim Takken
Related Documents :
11282769 - Exercise capacity predicts health status in alpha(1)-antitrypsin deficiency.
23979219 - Effect of endurance training on skeletal muscle myokine expression in obese men: identi...
20953749 - Influence of physical exercise on neuroimmunological functioning and health: aging and ...
10070599 - Correlates of exercise maintenance among people with mobility impairments.
24876539 - The impact of accelerometer and heart rate data on hypoglycemia mitigation in type 1 di...
18852019 - Relationship of serum brain-derived neurotrophic factor (bdnf) and health-related lifes...
8843129 - Myopia associated with hyperbaric oxygen therapy.
24997499 - A six-month exercise intervention in subclinical diabetic heart disease: effects on exe...
17394479 - Mechanomyography and electromyography during and after fatiguing shoulder eccentric con...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-9-2
Journal Detail:
Title:  Rheumatology (Oxford, England)     Volume:  -     ISSN:  1462-0332     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-9-5     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883501     Medline TA:  Rheumatology (Oxford)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Child Development and Exercise Center, Wilhelmina Children's Hospital, University Medical Center Utrecht, Utrecht, The Netherlands and Faculty of Human Movement Sciences, VU University Amsterdam, Amsterdam, The Netherlands.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Peripheral neuropathy in ANCA-associated vasculitis: outcomes from the European Vasculitis Study Gro...
Next Document:  Clinical significance of serum levels of sCD36 in patients with systemic sclerosis: preliminary data...