Document Detail

Safety and efficacy of cryoablation of atrial tachycardia with high risk of ablation-related injuries.
MedLine Citation:
PMID:  19174374     Owner:  NLM     Status:  MEDLINE    
AIMS: The purpose of this study was to evaluate the safety and efficacy of cryoablation as an alternative to radio frequency (RF) ablation in high-risk-located atrial tachycardia (AT). METHODS AND RESULTS: Between 2004 and 2007, 164 patients underwent catheter ablation due to AT at our institution. Twenty-six of these patients (22 women and 4 men), median age 58 years (range 14-76), were considered having high-risk-located AT and were treated by cryoablation. Seven patients had failed prior RF ablation due to high risk of complications. The AT foci distribution was: close to the AV node (n = 14), vicinity of the sinus node (n = 7), and crista terminalis adjacent to the phrenic nerve (n = 5). Cryomapping, using a 6 mm tip catheter, at -30 degrees C was performed before ablation with a goal temperature of -80 degrees C for 240 s. Acute success rate was achieved in 25/26 patients (96%). During a follow-up of 493 +/- 258 days, three patients had recurrences. Two of these underwent a second successful cryoablation procedure. Long-term success rate was 92%. Phrenic nerve palsy occurred in two patients with complete recovery after 1 day and 5 months, respectively. CONCLUSION: Cryoablation of high-risk-located AT foci is a safe and effective alternative to RF therapy.
Hamid Bastani; Per Insulander; Jonas Schwieler; Fariborz Tabrizi; Frieder Braunschweig; Göran Kennebäck; Nikola Drca; Bita Sadigh; Mats Jensen-Urstad
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Publication Detail:
Type:  Evaluation Studies; Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-01-26
Journal Detail:
Title:  Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology     Volume:  11     ISSN:  1532-2092     ISO Abbreviation:  Europace     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-04-29     Completed Date:  2009-06-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100883649     Medline TA:  Europace     Country:  England    
Other Details:
Languages:  eng     Pagination:  625-9     Citation Subset:  IM    
Department of Cardiology, Karolinska Institute, Karolinska University Hospital, S-141 86 Stockholm, Sweden.
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MeSH Terms
Atrioventricular Node / physiopathology*
Cryosurgery / adverse effects*,  methods*
Follow-Up Studies
Middle Aged
Phrenic Nerve / injuries*
Risk Factors
Sinoatrial Node / physiopathology*
Tachycardia, Ectopic Atrial / physiopathology,  surgery*
Treatment Outcome
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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